Continue Your Journey

21 Night Panama Canal

Departure Date
September 27, 2026
Multiple Dates Available
Supplier
Holland America
Destination
Panama Canal
Ship
Nieuw Amsterdam
Multiple

14 Night Alaska CRAZY DEAL!

Choose your departure date

Popular sailing!

Sail on a 21-night Panama Canal adventure with Holland America, beginning in Vancouver and ending in sunny Fort Lauderdale. This journey combines vibrant cities and tropical escapes, with visits to San Francisco and San Diego before heading south to Mexico’s Puerto Vallarta, Huatulco, and Puerto Chiapas. Explore Central America with stops in Puerto Quetzal and Acajutla, then experience the unforgettable passage through the Panama Canal—entering at Balboa, cruising its legendary locks, and exiting at Cristobal. The voyage continues with the historic charm of Cartagena and a day of relaxation on the white-sand beaches of Half Moon Cay, making for a truly remarkable journey from coast to coast.

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Ask About Great Single Pricing

*14 nights in the same stateroom: + $100pp (double occupancy) 

*14 nights in the same stateroom: +$200pp (single occupancy)

*There are only a limited amount of staterooms available on each sailing where moving is not going to be necessary.

Includes:

Your Cruise

  • 21 Night Panama Canal Cruise
  • Taxes

CruisePlus Booking Bonus

  • Up to $325 US per person Onboard Credit (varies by category)
CruisePlus Perks
Priority Access

» Priority check-in

» Priority access to specialty restaurant reservations

» Priority line at the Guest Services desk

» Priority line at the Shore Excursions desk

» Priority access to tenders ashore in select ports

» Priority disembarkation

Premium Dining

» Expanded 24-hour room service breakfast menu

» Pinnacle Class ships: Private dining venue for breakfast and dinner with an expanded menu

» All other ships: Priority seating in the Dining Room for breakfast and dinner with an expanded menu

Exclusive Amenities

» Complimentary stateroom upgrade

» Dedicated concierge service

» Welcome glass of sparkling wine on embarkation day

» Premium bathrobes

» Club Orange keycard

» Exclusive Club Orange tote bag (one per stateroom)

More information

Pricing
Neptune Suite Signature Suite Balcony Oceanview Obstructed Outside Inside
Cruise Only 14349 10299 6449 5499 5099 4549
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Call for pricing. 1.800.854.9664
Pricing is per person, based on double occupancy and in CAD. Additional terms & conditions apply.
Highlights & Sightseeing

Alcatraz Island

Once the home of famous gangsters like Al Capone, this legendary island in San Francisco Bay boasts a colorful history as the West Coast's first lighthouse, Civil War fortress, infamous federal prison, and bird sanctuary.

Huatulco

Oaxaca, a state in southern Mexico, has the town of Santa Mara Huatulco. Widespread pre-Hispanic ruins, including a ceremonial centre with a sizable stone temple and a ball court, may be seen nearby in the Parque Eco-Arqueológico Copalita. Jade and pottery artefacts from the location can be found in the Bocano del Ro Copalita Museum. Huatulco National Park, nearby on the Pacific coast, has beaches, coral reefs, and a wide variety of fauna.

Panama Canal & Historic Locks

The narrow isthmus separating the Atlantic from the Pacific Ocean had a colorful and turbulent history long before Ferdinand de Lesseps first dreamed of building a transcontinental canal. While transiting Gatun Lake, disembarkation is restricted to tours booked through the Cruise Line.

Half Moon Cay

Experience Holland America's pristine private island paradise in the Bahamas. Explore the island's stunning tropical sights by horse, kayak, or on foot.

Itinerary
Vancouver to Fort Lauderdale – 21-night Panama Canal Itinerary

Vancouver to Fort Lauderdale – 21-night Panama Canal Itinerary

Holland America Line | Vancouver, B.C., Canada → Fort Lauderdale, Florida, USA
Port / Destination Date Day Duration / Times Notes
Vancouver, B.C., CA 27SEP26 SUN DEPART 4:00PM PIER: CANADA PLACE PIER · CHECK IN STARTS AT 12:00PM
At Sea 28SEP26 MON AT SEA
At Sea 29SEP26 TUE AT SEA
San Francisco, California, US 30SEP26 WED ARRIVE 7:00AM · DEPART 9:00PM
At Sea 01OCT26 THU AT SEA
San Diego, California, US 02OCT26 FRI ARRIVE 7:00AM · DEPART 4:00PM PIER: B STREET TERMINAL
At Sea 03OCT26 SAT AT SEA
At Sea 04OCT26 SUN AT SEA
Puerto Vallarta, Mexico 05OCT26 MON ARRIVE 8:00AM · DEPART 5:00PM
At Sea 06OCT26 TUE AT SEA
Huatulco, Mexico 07OCT26 WED ARRIVE 10:00AM · DEPART 5:00PM
Puerto Chiapas, Mexico 08OCT26 THU ARRIVE 8:00AM · DEPART 5:00PM TIMES SUBJECT TO TIDAL CO
Puerto Quetzal, Guatemala 09OCT26 FRI ARRIVE 6:00AM · DEPART 8:00PM
Acajutla, El Salvador 10OCT26 SAT ARRIVE 7:00AM · DEPART 5:00PM
At Sea 11OCT26 SUN AT SEA
At Sea 12OCT26 MON AT SEA
Enter Panama Canal Balboa 13OCT26 TUE ARRIVE 5:00AM · DEPART 5:00AM CRUISING ONLY · TRANSIT TIMES ARE APPROXIMATE · PASSPORT REQUIRED
Cruising Panama Canal 13OCT26 TUE CRUISING ONLY
Exit Panama Canal Cristobal 13OCT26 TUE ARRIVE 7:00PM · DEPART 7:00PM CRUISING ONLY · TRANSIT TIMES ARE APPROXIMATE
Cartagena, Colombia 14OCT26 WED ARRIVE 12:00PM · DEPART 6:00PM
At Sea 15OCT26 THU AT SEA
At Sea 16OCT26 FRI AT SEA
RelaxAway Half Moon Cay, Bahamas 17OCT26 SAT ARRIVE 8:00AM · DEPART 2:00PM TENDER REQUIRED · WHEELCHAIR ACCESS LIMITED
Fort Lauderdale, Florida, US 18OCT26 SUN ARRIVE 7:00AM PIER: PORT EVERGLADES
Pricing is per person, in CAD and based on double occupancy. Additional terms & conditions apply.
Travel Insurance
For your protection, we strongly recommend that you purchase trip cancellation and medical insurance through Manulife.

However, no representation or description of the protection made by CruisePlus Management Ltd to you, constitutes a binding assurance or promise about the protection. We (CruisePlus) are not an insurance company and we do not have the responsibility for ensuring adherence to the insurance terms & conditions, submission, payment or adjustment of claims.

We strongly suggest you read through the insurance information provided upon purchase and email us with any questions.

Covid-19 is considered a known event and exclusions apply for most, if not all policies.
Terms & Conditions

New bookings only. Fares are per person in the currency noted (CAD), based on double occupancy, are capacity controlled, subject to availability at the time of booking and may be withdrawn without notice. Optional supplier charges may apply and are not included. Amenities, if offered, are available for the first two in a stateroom only & based on double occupancy unless specifically stated otherwise.

Hotel inventory is capacity controlled, and this offer may be pulled at any time without notice; Future Cruise Credits may not be combinable or be only partially combinable with advertised promotion; cruise line insurance may not be available to purchase on advertised offer.

Please note, this website may not reflect changes to offers in real time. Therefore, it is important you contact us in order to receive to a quote.

CruisePlus reserves the right to correct any human or electronic errors throughout the website at anytime. Before you book, be aware of Covid-19 restrictions and clearly understand insurance terms and conditions.

Offer Last Updated: Sep 09, 2025

$
6449
Balcony
per person
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per person
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per person
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1.800.854.9664
A+ BBB Rating
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